Precision-Crafted Custom Oligonucleotides for Every Application

From standard DNA/RNA to complex modifications, we deliver high-purity oligos tailored to your research and therapeutic needs — with fast turnaround, scalable production, and expert support.

Custom Oligonucleotide – Made to Order

Bio-Synthesis Inc. is a leading U.S.-based provider of custom oligonucleotide synthesis services. We specialize in custom DNA oligos, custom RNA oligos, and modified nucleotides for research, diagnostics, and therapeutic development from small to kilogram scales.

Our team manufactures oligonucleotides using phosphoramidite solid-phase synthesis, the gold standard for producing high-purity, sequence-specific DNA and RNA. Whether you need short primers, long oligos, or heavily modified nucleotides, we deliver quality and consistency at every scale.

Our Capabilities

  • Scalable production from mg to kilogram
  • OligoLS Research Discovery Oligo
  • OligoDX Diagnostic Oligo
  • OligoTX Preclinical Therapeutic Oligo
  • High-throughput DNA/RNA synthesis
  • long oligo synthesis
  • Specialized Oligos
  • Wide selection of purification options, formats, and packaging
  • Custom Formulation
  • Custom Quality Control

Applications of Oligos

Our oligos are used in a wide range of molecular biology and diagnostic applications

Life Sciences
  • PCR (Probes & Primers)
  • FISH and MERFISH Probes
  • FRET Probes
  • Molecular Beacons
  • Gene Editing
  • Novel Oligo Applications
Diagnostic
  • PCR (Probes & Primers)
  • Molecular Targeting (Aptamers)
  • Gene Editing
  • FISH & MERFISH Probes
  • NGS Adapters
  • Molecular Beacon
Therapeutic
  • Gene Silencing (siRNA & miRNA)
  • Antisense Oligonucleotide ASO
  • Gapmers
  • Molecular Targeting (Aptamers)
  • Gene Editing (Guide RNA)
  • Immunostimulatory

Contact Us

800 Mario Court
Lewisville, Texas 75077 USA
+1 800 227 0627
info@biosyn.com

Oligo Service

  • OligoLS™ RUO
  • Custom DNA
  • Custom RNA
  • Modification
  • OligoDX™ Diagnostic
  • OligoTX™ Therapeutic        

Why Choose BioSynthesis

Trusted by biotech leaders worldwide for over 45 years of delivering high quality, fast and scalable synthetic biology solutions.