Built for screening & immune profiling
Peptidomimetics, custom MHC peptide tetramers, and combinatorial peptide synthesis libraries engineered to accelerate discovery and lead optimization.
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Bio-Synthesis provides advanced design and discovery peptide platforms that support screening, immune profiling, and lead optimization. These services help you explore structure–activity relationships (SAR), stabilize bioactive motifs, and build reagents that enable high-confidence biological readouts.
Best-fit when you need
Recommendations on formats that match your screen or assay.
Libraries built for interpretability, not just size.
QC and documentation aligned to downstream workflows.
Use this table to map your discovery program to the right platform. For details, see the service sections below.
Related service pages (internal links)
For full options, pricing drivers, and examples, visit the dedicated pages:
Peptidomimetics are peptide-inspired designs that replicate key binding motifs while improving stability, protease resistance, or conformational control. They’re often used to stabilize a bioactive geometry that linear peptides do not maintain in solution.
Related: Peptidomimetics service page.
Custom MHC peptide tetramers are reagents used to identify and quantify antigen-specific T cells. Provide your epitope and allele information so we can build a tetramer matched to your immune profiling workflow.
Related: Custom MHC peptide tetramers service page.
Combinatorial peptide synthesis generates libraries that explore sequence space efficiently. Library design (positional scanning, focused libraries, motif constraints) determines how quickly you can interpret SAR and identify leads.
Related: Combinatorial peptide synthesis service page.
Choose peptidomimetics when you need improved stability, protease resistance, or a scaffold that better reproduces the bioactive conformation.
Provide the epitope sequence, MHC allele/class, desired fluorophore/label, quantity, and any special QC or documentation requirements.
Combinatorial peptide synthesis is the manufacturing approach used to generate peptide libraries. Library design determines how variants are distributed and screened.
Yes. Share your lead sequence and the positions you want to vary, plus the amino acid set or motif constraints.
Deliverables are aligned to the platform and downstream needs. Additional characterization and reporting can be added for complex products.
Yes. Labels and handles can be incorporated when planned into the design and compatible with the screening or immunology workflow.
Share your peptide sequence(s), labeling/handle type (isotope, cleavable linker, click chemistry), target purity/scale, and intended application. We’ll recommend practical specifications, platform strategy, and an appropriate synthesis/QC plan aligned to your screening, discovery, or immunology workflow. We’ll recommend practical specifications, platform strategy, and an appropriate synthesis/QC plan aligned to your screening, discovery, or immunology workflow.
Tip: If the peptide is hydrophobic/long/cysteine-rich, include that context so we can route the request to the right synthesis strategy.
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