High-loading, low-background conjugation for beads, plates, chips, and resins — engineered with EDC/NHS, maleimide, click, and biotin–streptavidin chemistries and supported by full QC.
Our surface & solid-support conjugation services immobilize antibodies, proteins, peptides, and oligonucleotides on magnetic beads, microplates, biosensor chips, and chromatography resins. We engineer high-loading, low-background surfaces using EDC/NHS, maleimide, click, and biotin–streptavidin chemistries with full QC support.
Our platform focuses on maximizing functional loading, minimizing non-specific binding, and ensuring robust lot-to-lot reproducibility. We match the right surface, linker length, and blocking strategy to your assay readout and sample matrix, then verify performance with targeted controls and QC analytics.
We also offer complementary carrier delivery systems (ADC & LNP) and bioconjugation services that integrate with these surface & solid-support conjugation projects.
Surfaces optimized for ELISA, bead-based immunoassays, NGS capture, and biosensors with defined coating density and blocking.
Use of spacers, PEGs, and tailored blocking buffers to maximize signal-to-noise across real-world samples.
Lot-controlled production with documentation suitable for kit developers, OEM partners, and regulated environments.
We apply a toolbox of well-characterized, assay-compatible chemistries to achieve robust attachment while preserving ligand function. Surface activation, ligand formulation, and reaction conditions are optimized together to minimize hydrolysis and side reactions.
For each project we recommend a primary chemistry plus alternatives, with small-scale scouting to confirm coating density, activity, and background under your exact assay conditions.
We design surfaces that align with your downstream readouts — fluorescence, chemiluminescence, colorimetric, MS, SPR/BLI, or imaging — and your real matrices (serum, plasma, lysate, etc.).
It depends on the assay format, throughput, and readout. Beads excel in automation and wash steps, plates are standard for ELISA, chips support microarrays and imaging, and resins are best for depletion/enrichment. We can recommend a platform based on your workflow and sample matrix.
For amine-rich proteins, EDC/NHS or epoxy/aldehyde works well; for cysteine-targeted or oriented installs we use maleimide–thiol; for modular systems we often use biotin–streptavidin or copper-free click. We’ll review your ligand sequence and format before proposing a route.
Yes. Background is often a combination of surface chemistry, coating density, and blocking/wash conditions. We can adjust ligand loading, introduce PEG spacers, and screen blocking buffers tailored to your sample matrix.
We routinely support kit and OEM partners with defined lot sizes, stability programs, and documentation suitable for regulated environments. We can align lot release criteria with your internal specifications.
Provide ligand details, preferred surface and format, assay readout, sample matrix, and any performance targets (e.g., dynamic range, CVs, shelf-life). If you have an existing assay, sharing your current protocol and pain points is very helpful.
Yes. We routinely work under NDA/MSA and treat all project materials and results as confidential. IP and ownership terms are defined up front as part of project onboarding.
Share your surface type, ligand details, assay format, and performance goals. We’ll recommend a conjugation route, surface chemistry, and QC package, then return a project quote.
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