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Peptide Modifications

1000+ peptide modifications with defined placement (N-term / internal / C-term) and analytics that confirm identity and purity.

Custom peptide modification services for labeling, PTMs, linkers, PEGylation, lipidation, and site-specific functional group chemistry—built to be practical, reproducible, and QC-verified.

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Overview

Bio-Synthesis offers a comprehensive peptide modification platform supporting more than 1000 structurally and functionally distinct peptide modifications with precise positional control. Our capabilities span N- and C-terminal modifications, side-chain functional group chemistry, backbone and conformational modifications, and architecture-level peptide design to support biological, analytical, and translational applications.

We provide unusual and non-canonical amino acid incorporation, site-defined cyclization strategies (disulfide, lactam, and backbone cyclization), and residue-selective chemistries targeting cysteine, lysine, tyrosine, and other functional side chains for controlled, site-specific conjugation.

Our platform further includes advanced conjugation and labeling solutions—such as fluorescent dyes, biotin and affinity tags, PEGylation, lipidation, and cleavable linker incorporation—along with click-chemistry–ready peptides (azide, alkyne, DBCO, BCN; CuAAC and copper-free), glycosylation and glycopeptide synthesis, a broad range of post-translational modifications (PTMs), and multivalent or branched peptide architectures.

Expert note: Successful peptide modification depends as much on site definition and sequence behavior as on the modification itself. All modified peptides are delivered with fit-for-purpose synthesis strategy, purification, and monoisotopic mass verification to ensure reproducibility and application-ready performance.

Defined placement

Choose N‑terminal, internal residue index, or C‑terminal placement for clean structures and easier QC.

Residue-selective

Functional group modification lives here: Cys/Lys/Tyr-selective chemistry for site-specific attachment.

Fit-for-purpose QC

We align purification/QC to the modification type (dyes/PEG/lipids/PTMs) to deliver application-ready peptides.

Request a Quote Browse 1000+ modifications

Related services: Click Chemistry Peptides, Isotope-Labeled Peptides, Cleavable Linker Peptides, Glycopeptides, Lipopeptides .

Service options we support (peptide modification categories)

Built for buyer clarity vs competitor lists: clear category naming, defined placement, and a searchable library that maps to how researchers order.

Terminal modifications (N- & C-terminus) acetylation • amidation • tags • reactive handles
N-terminal acetylation C-terminal amidation NHS / aldehyde handles biotin / dyes

Terminal caps and handles are the fastest way to control charge, stability, and conjugation site definition without changing the core sequence.

  • N-terminus: acetylation, formylation, labels, linkers, click-ready handles.
  • C-terminus: amidation, acids/esters, hydrazides, aldehydes (project-dependent).
  • Site-definition: recommended when comparing suppliers (reduces heterogeneity and simplifies QC).
Side-chain functional group chemistry (site-selective) Cys • Lys • Tyr (and more)
cysteine-specific chemistry lysine-selective chemistry tyrosine-selective chemistry site-specific thiol modification

Functional group modification belongs here: residue-selective reactions on thiols, amines, phenols, etc., to create a defined attachment point.

Cys (thiol)
  • Iodoacetamide / haloacetyl labeling
  • Maleimide conjugation
  • Disulfide formation & scrambling control
Lys / N-terminus (amine)
  • NHS-ester / activated ester coupling
  • Isothiocyanate labeling
  • Handle-assisted oxime/hydrazone (via installed aldehyde/aminooxy)
Tyr (phenol)
  • Electrophilic aromatic substitution (handle-dependent)
  • Diazonium/azo labeling (use-case dependent)
  • Orthogonal handle installation for strict site control

Also possible (project-dependent): Trp-, His-, Asp/Glu-, Ser/Thr-selective strategies, often enabled by orthogonal handles.

Post-translational modifications (PTM peptides) phosphorylation • acetylation • methylation • sulfation • glyco
phospho-serine phospho-tyrosine acetyl-lysine methyl-arginine sulfotyrosine O-GlcNAc

PTM peptides are used for enzyme assays, antibody validation, epitope mapping, and quantitative LC–MS/MS workflows.

  • Phospho: Ser/Thr/Tyr.
  • Acetyl / methyl: Lys/Arg and N-terminus.
  • Sulfation / glyco: Tyr sulfation; O-GlcNAc/GalNAc (project-dependent).
Conjugations that shift properties PEGylation • lipidation • dyes • chelators • affinity tags
PEGylated peptides lipidated peptides fluorescent labeling biotin peptide DOTA / chelators

Lipidation is a type/class of modification; each specific lipid (palmitoyl, myristoyl, stearyl, etc.) is an individual modification.

  • Half-life / PK: PEG, lipids, albumin-binding strategies (architecture-dependent).
  • Imaging: fluorophores, quenchers, chelators (e.g., DOTA).
  • Capture: biotin and affinity tags for pull-down/enrichment.
Analytical & QC-driven modifications stable isotopes • TMT • quantitation standards
stable isotope-labeled peptides monoisotopic mass LC–MS/MS standards TMT tags

For quantitative proteomics and method development, we support light/heavy pairs and reporting aligned to exact-mass (monoisotopic) verification.

Application-driven peptide modifications

Half-life & PK enhancement
  • PEGylation (size/clearance control)
  • Lipidation (membrane/albumin association)
  • Architecture-driven designs (project-dependent)
Imaging & detection
  • Fluorophores / quenchers
  • Chelators (e.g., DOTA)
  • Photoreactive probes (use-case dependent)
Affinity & capture
  • Biotin and affinity tags
  • Handle-based pull-down
  • Defined stoichiometry for reproducibility
Targeting & cell uptake
  • CPP/fatty-acid hybrids (architecture-dependent)
  • Receptor-targeting motifs + payload handles
  • Conjugation site selection to preserve activity
PTM peptides
  • Phospho (Ser/Thr/Tyr)
  • Acetyl / methyl (Lys/Arg)
  • Sulfation, O-GlcNAc/GalNAc (project-dependent)
Analytical & QC-driven
  • Stable isotope standards
  • TMT tags
  • Exact-mass (monoisotopic) confirmation

Expert FAQs: PTM & Lipidated Peptides

Why do PTM peptides often fail at other suppliers?
PTM peptides frequently fail due to on-resin aggregation, incomplete modification, or PTM instability. We mitigate this using orthogonal protection, stepwise validation, and purification methods tailored to each PTM class (e.g., phospho, sulfated, acetylated peptides).
Is lipidation just attaching a fatty acid?
No. Lipidation is an architecture-level modification. The lipid type, attachment site (N-terminus vs side-chain), linker choice, and sequence hydrophobicity all determine solubility, aggregation risk, and biological performance. We design lipidated peptides accordingly.
How do you ensure site-specific modification?
Site specificity is achieved through single-handle design, residue-selective chemistry (e.g., cysteine-only), and protection strategies that prevent off-target labeling—critical for conjugates and quantitative studies.
Do modifications affect MS confirmation?
Yes. Many modifications alter ionization or fragmentation. We adjust MS methods accordingly and report monoisotopic or exact mass confirmation whenever applicable.

Modification library (search + sortable)

0 rows
● Available position ○ Not available … Repeats across sequence positions
Type Name Abbreviation or alternative name Position within sequence Graphical representation of available positions
Special AAs 2-(4'-Pentenyl)alanine - [A(pentenyl)] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2,3-Diaminopropionic acid - DAP [DAP] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2-Amino-4-thiazolinic acid - [2-Amino-4-thiazolinyl] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2-Indanyl-Glycine - Igl [Igl] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2-Methyl-D-Tryptophan - [D-W(2-Me)] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2-Naphthyl-Alanine - 2-Nal [2-Nal] N-term, Internal, C-term ●●●●...●●●●
Special AAs 2-Naphthyl-D-Alanine - D-2-Nal [D-2-Nal] N-term, Internal, C-term ●●●●...●●●●
Special AAs 3,3-Diphenyl-Alanine - [A(F2)] N-term, Internal, C-term ●●●●...●●●●
Special AAs 3,4-Dihydroxy-Phenylalanine - [F(OH)2] N-term, Internal, C-term ●●●●...●●●●
Special AAs 5,5-Dimethyl-Proline - [P(Me2)] N-term, Internal, C-term ●●●●...●●●●
Special AAs 5-Hydroxy-Tryptophan - [W(OH)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Allyl-Glycine - 2-Aminopent-4-enoic acid [G(allyl)] N-term, Internal, C-term ●●●●...●●●●
Special AAs alpha-Allylalanine - [Allyl-A] N-term, Internal, C-term ●●●●...●●●●
Special AAs alpha-aminoadipic acid - Aad [Aad] N-term, Internal, C-term ●●●●...●●●●
Special AAs alpha-t-butylglycine - [G(tBu)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Aminobenzoic acid - Abz [Abz] N-term, Internal, C-term ●●●●...●●●●
Special AAs Aminobutyric acid - Abu [Abu] N-term, Internal, C-term ●●●●...●●●●
Special AAs Aminocyclohexyl carbox. acid - Ac6c [Ac6c] N-term, Internal, C-term ●●●●...●●●●
Special AAs Aminoisobutyric acid - Aib [Aib] N-term, Internal, C-term ●●●●...●●●●
Special AAs Asp beta-methyl ester - Asp(OMe) [D(OMe)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Asp(Isopropylamide) - [D(Isopropylamide)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Azetidine-2-carboxylic acid - Aze [Aze] N-term, Internal, C-term ●●●●...●●●●
Special AAs Canavanine - Cav [Cav] N-term, Internal, C-term ●●●●...●●●●
Special AAs Citrulline - [Cit] N-term, Internal, C-term ●●●●...●●●●
Special AAs Cyclopentyl-Glycine - [G(cyclopentyl)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Cysteic acid - Cya [Cya] N-term, Internal, C-term ●●●●...●●●●
Special AAs Cysteine sulfonate - [C(SO3H)] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-2-Indanyl-Glycine - D-Igl [D-Igl] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-4-Hydroxyphenly-Glycine - D-Hpg [D-Hpg] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Alanine - *A N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Amino Acid - [D-aa] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Arginine - *R N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Asparagine - *N N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Aspartic acid - *D N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Cysteine - *C N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Glutamic acid - *E N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Glutamine - *Q N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Histidine - *H N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Homocysteine - [D-Homocys] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Homoserine - [D-Homoser] N-term, Internal, C-term ●●●●...●●●●
Special AAs Diaminotrioxatridecan suc. ac. - TTDS [TTDS] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Isoleucine - *I N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Leucine - *L N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Lysine - *K N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Methionine - *M N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Ornithine - [D-Orn] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Phenylalanine - *F N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Proline - *P N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Serine - *S N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Threonine - *T N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Tryptophan - *W N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Tyrosine - *Y N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Valine - *V N-term, Internal, C-term ●●●●...●●●●
Special AAs Formylglycine - [G(CHO)] N-term, Internal, C-term ●●●●...●●●●
Special AAs gamma-Carboxyglutamic acid - Gla [Gla] N-term, Internal, C-term ●●●●...●●●●
Special AAs Gamma-Glu, amidated - Gla, amidation at side chain [Gla amide] N-term, Internal, C-term ●●●●...●●●●
Special AAs Glu gamma-methyl ester - Glu(OMe) [E(OMe)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Homo-Citrulline - [Homocit] N-term, Internal, C-term ●●●●...●●●●
Special AAs Homophenylalanine - [HomoF] N-term, Internal, C-term ●●●●...●●●●
Special AAs Homoserine - [Homoser] N-term, Internal, C-term ●●●●...●●●●
Special AAs Hydroxy-Proline - Hyp [Hyp] N-term, Internal, C-term ●●●●...●●●●
Special AAs Hyposine - Hpu [Hpu] N-term, Internal, C-term ●●●●...●●●●
Special AAs Isoaspartic acid - 0 N-term, Internal, C-term ●●●●...●●●●
Special AAs Kynurenine - Kyn [Kyn] N-term, Internal, C-term ●●●●...●●●●
Special AAs Mercaptoacetic acid - Thioglycolic acid [Mercaptoacetyl] N-term, Internal, C-term ●●●●...●●●●
Special AAs Mercaptopropionic acid - Mpa [Mpa] N-term, Internal, C-term ●●●●...●●●●
Special AAs Methionine-sulfone - [M(O2)] N-term, Internal, C-term ●●●●...●●●●
Special AAs Methionine-sulfoxide - [M(O)] N-term, Internal, C-term ●●●●...●●●●
Special AAs N-Formylkynurenine - [Formyl-Kyn] N-term, Internal, C-term ●●●●...●●●●
Special AAs Norleucine - [Nle] N-term, Internal, C-term ●●●●...●●●●
Special AAs Norvaline - 2-Aminopentanoic acid, Nva [Nva] N-term, Internal, C-term ●●●●...●●●●
Special AAs Octahydroindole carbox. acid - [Oic] N-term, Internal, C-term ●●●●...●●●●
Special AAs Ornitine - [Orn] N-term, Internal, C-term ●●●●...●●●●
Special AAs para-Acetylphenylalanine - pAF [para-Ac-Phe] N-term, Internal, C-term ●●●●...●●●●
Special AAs Phenylglycine - Phg [Phg] N-term, Internal, C-term ●●●●...●●●●
Special AAs Pyroglutamic acid - Pyr [Pyr] N-term, Internal, C-term ●●●●...●●●●
Special AAs Selenocysteine - Sec [Sec] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Alanine - [*A] N-term, Internal, C-term ●●●●...●●●●
Special AAs β-Cyclohexyl-Alanine - Cha [Cha] N-term, Internal, C-term ●●●●...●●●●
Special AAs β-cyclohexyl-D-Alanine - D-Cha [D-Cha] N-term, Internal, C-term ●●●●...●●●●
Special AAs Tetrahydroisquinol.carb.acid - Tic [Tic] N-term, Internal, C-term ●●●●...●●●●
Special AAs Thiazolidine-4-carboxylic acid - Thz [Thz] N-term, Internal, C-term ●●●●...●●●●
Special AAs D-Glutamic acid - [*E] N-term, Internal, C-term ●●●●...●●●●
PTM 1-Methyl-Tryptophan - [W(1-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM 2,6-Dimethyl-Tyrosine - [Y(Me2)] N-term, Internal, C-term ●●●●...●●●●
PTM 2-Methylproline - [P(2-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM 2-Methyl-Tryptophan - [2-Me-Trp] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Arginine (asym.) - [R(Me)2-asym] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Arginine (sym.) - [R(Me)2-sym] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Cysteine - Penicillamine [Pen] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Lysine - [K(Me)2] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Phenylalanine - [F(Me)2] N-term, Internal, C-term ●●●●...●●●●
PTM Dimethyl-Valine - [V(Me)2] N-term, Internal, C-term ●●●●...●●●●
PTM Methyl-Arginine - [R(Me)] N-term, Internal, C-term ●●●●...●●●●
PTM Methyl-Lysine - [K(Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Alanine - [Ala(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Glycine - [G(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Leucine - [L(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Phenylalanine - [F(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Tyrosine - [Y(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM N-Methyl-Valine - [V(N-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM Phosphono-Phenylalanine - [F(PO3H2)] N-term, Internal, C-term ●●●●...●●●●
PTM Phospho-Serine - [S(PO3H2)] N-term, Internal, C-term ●●●●...●●●●
PTM Phospho-Threonin - [T(PO3H2)] N-term, Internal, C-term ●●●●...●●●●
PTM Phospho-Tyrosin - [Y(PO3H2)] N-term, Internal, C-term ●●●●...●●●●
PTM β-GalNAc-Threonine - [T(β-GalNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM β-GlcNAc-Asparagine - [N(β-GlcNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM β-GlcNAc-Serine - [S(β-GlcNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM α-GlcNAc-Threonine - [T(α-GlcNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM Sulfuryl-Serine - [S(SO3H)] N-term, Internal, C-term ●●●●...●●●●
PTM Sulfuryl-Threonine - [T(SO3H)] N-term, Internal, C-term ●●●●...●●●●
PTM Sulfuryl-Tyrosine - [Y(SO3H)] N-term, Internal, C-term ●●●●...●●●●
PTM Trimethyl-Arginine - [R(Me3)] N-term, Internal, C-term ●●●●...●●●●
PTM Trimethyl-Lysine - [K(Me)3] N-term, Internal, C-term ●●●●...●●●●
PTM α-GalNAc-Serine - [S(α-GalNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM α-GalNAc-Threonine - [T(α-GalNAc)] N-term, Internal, C-term ●●●●...●●●●
PTM α-Mannosyl-Serine - [S(α-Mannosyl)] N-term, Internal, C-term ●●●●...●●●●
PTM α-Mannosyl-Threonine - [T(α-Mannosyl)] N-term, Internal, C-term ●●●●...●●●●
PTM α-Methyl Aspartic acid - [D(α-Me)] N-term, Internal, C-term ●●●●...●●●●
PTM α-Methyl Glutamic acid - [E(α-Me)] N-term, Internal, C-term ●●●●...●●●●
Misc 1-Adamantanecarbonyl - 1-Adamantanecarbonyl-NH N-term ●●●●...●●●●
Misc 2,4,6-Trinitrophenyl - TNP TNP-NH N-term ●●●●...●●●●
Misc 2-Furoyl - 2-Furoyl-NH N-term ●●●●...●●●●
Misc 2-Naphtoic acid - Naphtyl-NH N-term ●●●●...●●●●
Misc 3-(Maleimido)propionyl - Maleimide-NH N-term ●●●●...●●●●
Misc 3,5-Diiodo-Tyrosine - [Y(I)2] N-term, Internal, C-term ●●●●...●●●●
Misc 3-Chloro-Tyrosine - [Y(Cl)] N-term, Internal, C-term ●●●●...●●●●
Misc 3-nitro-2-pyridylthio-L-Cys - [C(Npys)] N-term, Internal, C-term ●●●●...●●●●
Misc 3-Nitro-Indole - [3-Nitro-Indole] N-term, Internal, C-term ●●●●...●●●●
Misc 3-Nitro-Pyrrol - [3-Nitro-Pyrrol] N-term, Internal, C-term ●●●●...●●●●
Misc 3-Nitro-Tyrosine - [Y(NO2)] N-term, Internal, C-term ●●●●...●●●●
Misc 4-Methylthio-2-oxobutanoic ac. - [H3C-S-CH2-CH2-CO-CO-NH] N-term ●●●●...●●●●
Misc 4-nitrobenzo-2-oxa-1,3-diazole - NBD NBD-NH N-term ●●●●...●●●●
Misc 4-Pentynoic acid - 4-Pentynoic acid-NH N-term ●●●●...●●●●
Misc 4-Phenylazophenol - O-PAP CO-PAP C-term ●●●●...●●●●
Misc 6-Bromo-D/L-Tryptophan - [D/L-W(Br)] N-term, Internal, C-term ●●●●...●●●●
Misc 6-Cloro-Tryptophan - [W(Cl)] N-term, Internal, C-term ●●●●...●●●●
Misc Acetylation - Acetyl-NH N-term ●●●●...●●●●
Misc Aldehyde - CHO C-term ●●●●...●●●●
Misc Amidation - CONH2 C-term ●●●●...●●●●
Misc Amino nitrophenyl prop. acid - [Amino nitrophenyl prop. acid] N-term, Internal, C-term ●●●●...●●●●
Misc Amino-nitrophenyl propion. ac. - ANP-linker [ANP] N-term, Internal, C-term ●●●●...●●●●
Misc Aminooxy acetyl - H2N-O-CH2-CO-NH N-term ●●●●...●●●●
Misc Benzoyl - Bz Benzoyl-NH N-term ●●●●...●●●●
Misc Benzyloxy carbonyl - Cbz, Z Z-NH N-term ●●●●...●●●●
Misc Biotin - Biotin-NH N-term ●●●●...●●●●
Misc Biotin - Ethylenediamine-Biotin CO-NH-CH2-CH2-NH-Biotin C-term ●●●●...●●●●
Misc Biotin-SS-linker - Biotin-SS-NH N-term ●●●●...●●●●
Misc Bis(aminoethyl)ethylene glycol - CO-NH-(CH2-CH2-O)2-CH2-CH2-NH2 C-term ●●●●...●●●●
Misc Brom acetic acid - BrCH2CO-NH N-term ●●●●...●●●●
Misc Chloroethylene - CMK CMK C-term ●●●●...●●●●
Misc Cys(4-Methoxytrityl) - Cys(MMT) [C(Mmt)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Acetamidomethyl) - Cys(Acm) [C(Acm)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Carbamidomethyl) - Cys(CAM) / Cys(CH2CONH2) [C(Cam)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Carboxymethyl) - Cys(CMC) / Cys(CH2COOH) [C(Cmc)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(di(palmitoyloxy)-propyl) - Cys(Pam2) [C(Pam2)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Farnesyl) - [C(Farnesyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(HRP) - Cys(horseradish peroxidase) [C(HRP)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(MTSL) - [C(MTSL)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Myristyl) - Cys(CH2(CH2)12CH3) [C(Myristyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(Palmitoyl) - [C(Palm)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Butyl) - [C(S-But)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Ethyl) - [C(S-Et)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Isobutyl) - [C(S-Isobut)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Isopropyl) - [C(S-Isoprop)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Methyl) - [C(S-Me)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Pentyl) - [C(S-Pentyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-Propyl) - [C(S-Prop)] N-term, Internal, C-term ●●●●...●●●●
Misc Cys(S-tert-Butyl) - [C(S-tert-But] N-term, Internal, C-term ●●●●...●●●●
Misc Cysteamide - Cysteamide C-term ●●●●...●●●●
Misc Decanoyl - Decanoyl-NH N-term ●●●●...●●●●
Misc Desthiobiotin - Desthiobiotin-NH N-term ●●●●...●●●●
Misc Digoxigenin - Digoxigenin-NH N-term ●●●●...●●●●
Misc DOTA - [DOTA] N-term ●●●●...●●●●
Misc Ethylamide - N-Ethyl CONH(C2H5) C-term ●●●●...●●●●
Misc Ethylester - O-Ethyl COOEt C-term ●●●●...●●●●
Misc Fmoc - Fmoc-NH N-term ●●●●...●●●●
Misc Formyl - Formyl-NH N-term ●●●●...●●●●
Misc Glu(Arg) - Arg at side chain of Glu [Glu(Arg)] N-term, Internal, C-term ●●●●...●●●●
Misc Homoserine lactone - [Homoser lactone] C-term ●●●●...●●●●
Misc HRP - CO-NH -HRP C-term ●●●●...●●●●
Misc HRP - HRP-NH N-term ●●●●...●●●●
Misc Hydrazide - CO-NH -NH2 C-term ●●●●...●●●●
Misc Hydrazine-succinyl - H2N-NH-CO-CH2-CH2-CO-NH- N-term ●●●●...●●●●
Misc Iodoacetyl - IH2C-CO- N-term ●●●●...●●●●
Misc Lys(2-Aminooxy acetic acid) - Lys(Aoa) [K(Aoa)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Acetyl) - [K(Ac)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Ahx-Biotin) - [K(Ahx-Biotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Ahx-SS-Biotin) - [K(Ahx-SS-Biotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Biotin) - [K(Biotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Boc) - [K(Boc)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Butyryl) - [K(Butyryl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Desthiobiotin) - [K(Desthiobiotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Digoxigenin] - [K(Digoxigenin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(DST-PEG 2-Biotin) - [K(DST-PEG 2-Biotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Ferrocene) - [K(Ferrocene)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Formyl) - [K(Formyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(GG) - Ubiquitin [K(GG)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(GGRLR) - [K(GGRLR)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Glutaryl) - [K(Glutaryl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Lipoyl) - [K(Lipoyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(NIP) - [K(NIP)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Palmitoyl) - [K(Palmitoyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Propionyl) - [K(Propionyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Pyrofolate) - [K(Pyrofolate)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Stearyl) - [K(Stearyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(Succinyl) - [K(Succinyl)] N-term, Internal, C-term ●●●●...●●●●
Misc Lys(TFA) - Lysine(Trifluoroacetyl) [K(TFA)] N-term, Internal, C-term ●●●●...●●●●
Misc Maleimide - via SMCC Maleimide-NH N-term ●●●●...●●●●
Misc Methanethiosulfonate - MTS MTS-NH N-term ●●●●...●●●●
Misc Methoxysuccinyl - H3C-O-CO-CH2-CH2-CO-NH N-term ●●●●...●●●●
Misc Methylamide - N-Methyl CO-NH(CH3) C-term ●●●●...●●●●
Misc Methylester - O-Methyl COOMe C-term ●●●●...●●●●
Misc Myristoyl - Myristoyl-NH N-term ●●●●...●●●●
Misc N-Hydroxysuccinimid ester - NHS CO-NHS C-term ●●●●...●●●●
Misc Orn(Biotin) - [Orn(Biotin)] N-term, Internal, C-term ●●●●...●●●●
Misc Palmitoyl - Palmitoyl-NH N-term ●●●●...●●●●
Misc para-Bromo-D-Phenylalanine - [D-F(4-Br)] N-term, Internal, C-term ●●●●...●●●●
Misc para-Chloro-Phenylalanine - [F(4-Cl)] N-term, Internal, C-term ●●●●...●●●●
Misc para-Iodo-Phenylalanine - [F(I)] N-term, Internal, C-term ●●●●...●●●●
Misc para-Nitro-Phenylalanine - [F(NO2)] N-term, Internal, C-term ●●●●...●●●●
Misc Phenylacetic acid - Paa Paa-NH N-term ●●●●...●●●●
Misc Photo-Leucine - [Photo-L] N-term, Internal, C-term ●●●●...●●●●
Misc Photo-Methionine - [Photo-M] N-term, Internal, C-term ●●●●...●●●●
Misc p-tosyl-Gly - [p-tosyl-G] N-term ●●●●...●●●●
Misc S-Acetylmercaptosuccinyl - SAMSA SAMSA-NH N-term ●●●●...●●●●
Misc Ser(Acetyl) - [S(Ac)] N-term, Internal, C-term ●●●●...●●●●
Misc Ser(Octanoyl) - [S(Oct)] N-term, Internal, C-term ●●●●...●●●●
Misc Stearyl - Stearyl-NH N-term ●●●●...●●●●
Misc Succinyl - Succinyl-NH N-term ●●●●...●●●●
Misc t-Butylester - COOtBu C-term ●●●●...●●●●
Misc tert. Butoxycarbonyl - Boc Boc-NH N-term ●●●●...●●●●
Misc Thiobenzyl - CO-S(Bzl) C-term ●●●●...●●●●
Misc Thiopropionyl - Tpa Tpa-NH N-term ●●●●...●●●●
Misc trans-Cinnamoyl - Cinnamoyl-NH N-term ●●●●...●●●●
Misc Tyr(Palmitoyl) - [Y(Palm)] N-term, Internal, C-term ●●●●...●●●●
Linkers 12-Aminododecanoic acid - Ado [Ado] N-term, Internal, C-term ●●●●...●●●●
Linkers 5-Aminopentanoic acid - Aminovaleric acid (Ava) [Ava] N-term, Internal, C-term ●●●●...●●●●
Linkers 6-Aminohexanoic acid (Ahx) - Aminocaproic acid (Aca) [Ahx] N-term, Internal, C-term ●●●●...●●●●
Linkers 8-Aminooctanoic acid - Aoc [Aoc] N-term, Internal, C-term ●●●●...●●●●
Linkers Cys(PEG 40000) - [C(PEG 40000)] N-term, Internal, C-term ●●●●...●●●●
Linkers Methyl-PEG12 - MS(PEG)12 MS(PEG)12-NH N-term ●●●●...●●●●
Linkers Methyl-PEG24 - MS(PEG)24 MS(PEG)24-NH N-term ●●●●...●●●●
Linkers PEG 12 (40 atoms) - Amino-PEG-acid [PEG 12] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 2 (9 atoms) - 8-Amino-3,6-dioxaoctanoic acid [PEG 2] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 20,000 - PEG 20,000-NH N-term ●●●●...●●●●
Linkers PEG 2000 - Amino-PEG-acid [PEG 2000] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 3 (13 atoms) - Amino-trioxadodecanoic acid [PEG 3] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 4 (16 atoms) - Amino-PEG-acid [PEG 4] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 5 (19 atoms) - Amino-PEG-acid [PEG 5] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 5000 - CO-PEG 5000 C-term ●●●●...●●●●
Linkers PEG 5000 - Amino-PEG-acid [PEG 5000] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 6 (22 atoms) - Amino-PEG-acid [PEG 6] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG 8 (28 atoms) - Amino-PEG-acid [PEG 8] N-term, Internal, C-term ●●●●...●●●●
Linkers PEG-4 Azide - N3-PEG4-NH N-term ●●●●...●●●●
Isotopic Heavy Ala (13C3;15N) - [A(13C3; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Ala (D3) - [A(D3)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Arg (13C6) - [R(13C6)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Arg (13C6;15N4) - [R(13C6; 15N4)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Asn (13C4;15N2) - [N(13C4; 15N2)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Asp (13C4;15N - [D(13C4; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Gln (13C5;15N2) - [Q(13C5;15N2)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Glu (13C5;15N) - [E(13C5; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Gly (13C2;15N) - [G(13C2; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy His (15N3) - [His(15N3)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Ile (13C6;15N) - [I(13C6; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Leu (13C1) - [L(13C1)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Leu (13C6) - [L(13C6)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Leu (13C6;15N) - [L(13C6; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Leu (D10) - [L(D10)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Leu (D3) - [L(D3)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Lys (13C6) - [K(13C6)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Lys (13C6;15N2) - [K(13C6; 15N2)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Phe (13C9;15N) - [F(13C9; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Pro (13C5;15N) - [P(13C5; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Ser (13C3;15N) - [S (13C3;15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Ser (D3) - [S(D3)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Thr(13C4;15N) - [T(13C4;15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Trp (13C11;15N2) - [W (13C11;15N2)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Tyr (13C9;15N) - [Y (13C9; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Val (13C5) - [V(13C5)] N-term, Internal, C-term ●●●●...●●●●
Isotopic Heavy Val (13C5;15N) - [V(13C5; 15N)] N-term, Internal, C-term ●●●●...●●●●
Isotopic L-tyrosine-phenyl-d4 - deuterated Tyr [Tyr(D4)] N-term, Internal, C-term ●●●●...●●●●
Isotopic TMT6-126 - TMT6-126-NH N-term ●●●●...●●●●
Isotopic TMT6-127 - TMT6-127-NH N-term ●●●●...●●●●
Isotopic TMT6-128 - TMT6-128-NH N-term ●●●●...●●●●
Isotopic TMT6-129 - TMT6-129-NH N-term ●●●●...●●●●
Isotopic TMT6-130 - TMT6-130-NH N-term ●●●●...●●●●
Isotopic TMT6-131 - TMT6-131-NH N-term ●●●●...●●●●
Immunization Blue Carrier Protein - CO-NH -Blue Carrier Protein C-term ●●●●...●●●●
Immunization BSA - CO-BSA C-term ●●●●...●●●●
Immunization BSA via Glutaraldehyde - BSA-NH N-term ●●●●...●●●●
Immunization Cys(BSA) - [C(BSA)] N-term, Internal, C-term ●●●●...●●●●
Immunization Cys(KLH) - [C(KLH)] N-term, Internal, C-term ●●●●...●●●●
Immunization Cys(OVA) - [C(OVA)] N-term, Internal, C-term ●●●●...●●●●
Immunization KLH - CO-KLH C-term ●●●●...●●●●
Immunization KLH via Glutaraldehyde - KLH-NH N-term ●●●●...●●●●
Immunization Lys(BSA) - [K(BSA] N-term, Internal, C-term ●●●●...●●●●
Immunization Lys(KLH) - [K(KLH] N-term, Internal, C-term ●●●●...●●●●
Immunization MAP 16 - Crude 8-20 aa, at C-term. only MAP 16 C-term ●●●●...●●●●
Immunization MAP 4 - Crude 8-20 aa, at C-term. only MAP 4 C-term ●●●●...●●●●
Immunization MAP 8 - Crude 8-20 aa, at C-term. only MAP 8 C-term ●●●●...●●●●
Immunization OVA - CO-OVA C-term ●●●●...●●●●
Dye (2,4-Dinitrophenyl)-Glycine - (2,4-DNP)-Gly DNP-NH-G N-term ●●●●...●●●●
Dye 2,4-Dinitrophenyl - DNP CO-DNP C-term ●●●●...●●●●
Dye 2,4-Dinitrophenyl - DNP DNP-NH N-term ●●●●...●●●●
Dye 5/6-Carboxyfluorescein - 5/6-FLUO 5/6-Fluorescein-NH N-term ●●●●...●●●●
Dye 5/6-Tetramethylrhodamine - 5/6-TAMRA 5/6-TAMRA-NH N-term ●●●●...●●●●
Dye 5-Carboxyfluorescein - 5-FLUO 5-Fluorescein-NH N-term ●●●●...●●●●
Dye 5-Tetramethylrhodamine - 5-TAMRA 5-TAMRA-NH N-term ●●●●...●●●●
Dye 6-Carboxyfluorescein - 6-FLUO 6-Fluorescein-NH N-term ●●●●...●●●●
Dye 6-Tetramethylrhodamine - 6-TAMRA 6-TAMRA-NH N-term ●●●●...●●●●
Dye 7-Amino-4-methylcoumarin - AMC CO-AMC C-term ●●●●...●●●●
Dye Ala(2-Bacd) - benzo[b]acridin-12(5H)-on-2-yl [Ala(2-Bacd)] N-term, Internal, C-term ●●●●...●●●●
Dye Amino-trifluoromethyl-coumarin - AFC CO-AFC C-term ●●●●...●●●●
Dye ATTO 647N - ATTO 647N-NH N-term ●●●●...●●●●
Dye Cy7 - Cy7-NH N-term ●●●●...●●●●
Dye Cys(5/6-TAMRA) - [C(5/6-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(5-TAMRA) - [C(5-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(6-TAMRA) - [C(6-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(acetamido-fluorescein) - [C(acetamido-fluorescein)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(AEDANS) - [C(AEDANS)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(Allophycocyanine) - [C(Allophycocyanine)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(DY 555) - [C(DY 555)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(DY 647P1) - [C(DY 647P1)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(DY 649) - [C(DY 649)] N-term, Internal, C-term ●●●●...●●●●
Dye Cys(DYQ660) - [Cys(DYQ660)] N-term, Internal, C-term ●●●●...●●●●
Dye Dabcyl - Dabcyl-NH N-term ●●●●...●●●●
Dye Dabsyl - Dabsyl-NH N-term ●●●●...●●●●
Dye Dansyl - CO-Dansyl C-term ●●●●...●●●●
Dye Dansyl - Dansyl-NH N-term ●●●●...●●●●
Dye DAP(DNP) - DNP at Diaminopropionic acid [DAP(DNP)] N-term, Internal, C-term ●●●●...●●●●
Dye DAP(DY 647) - DY 647 at Diaminopropionic ac. [DPA(DY-647)] N-term, Internal, C-term ●●●●...●●●●
Dye DAP(DyLight 488) - DyLight 488 at Diaminoprop. ac [DPA(DY 488)] N-term, Internal, C-term ●●●●...●●●●
Dye DAP(NMA) - NMA at Diaminopropionic acid [DAP(NMA)] N-term, Internal, C-term ●●●●...●●●●
Dye Dinitrophenyl-Ethylenediamine - EDDnp CO-EDDnp C-term ●●●●...●●●●
Dye D-Lys(5/6-Fluorescein) - [D-K(5/6-Fluorescein)] N-term, Internal, C-term ●●●●...●●●●
Dye D-Lys(5/6-TAMRA) - [D-Lys(5/6-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye DY 495 - DY 495-NH N-term ●●●●...●●●●
Dye DY 505 - DY 505-NH N-term ●●●●...●●●●
Dye DY 530 - DY 530-NH N-term ●●●●...●●●●
Dye DY 547 - DY 547-NH N-term ●●●●...●●●●
Dye DY 549 - DY 549-NH N-term ●●●●...●●●●
Dye DY 630 - DY630-NH N-term ●●●●...●●●●
Dye DY 633 - DY 633-NH N-term ●●●●...●●●●
Dye DY 635 - DY 635-NH N-term ●●●●...●●●●
Dye DY 647 - DY 647-NH N-term ●●●●...●●●●
Dye DY 647 - aminomodified CO-DY 647 C-term ●●●●...●●●●
Dye DY 649 - DY 649-NH N-term ●●●●...●●●●
Dye DY 649P1 - aminomodified CO-DY 649P1 N-term ●●●●...●●●●
Dye DY 650 - DY650-NH N-term, Internal, C-term ●●●●...●●●●
Dye DY 680 - DY 680-NH N-term ●●●●...●●●●
Dye DY 682 - DY 682-NH N-term ●●●●...●●●●
Dye DY 750 - DY 750-NH N-term ●●●●...●●●●
Dye DY 750 - CO-DY 750 C-term ●●●●...●●●●
Dye DY 751 - DY 751-NH N-term ●●●●...●●●●
Dye DY 800 - DY 800-NH N-term ●●●●...●●●●
Dye DyLight 488 - DY 488-NH N-term ●●●●...●●●●
Dye DyLight 504Q - DyLight 504Q-NH N-term ●●●●...●●●●
Dye DyLight 543Q - DyLight 543Q-NH N-term ●●●●...●●●●
Dye DyLight 554-R1 - DyLight 554-R1-NH N-term ●●●●...●●●●
Dye DyLight 683Q - DyLight 683Q-NH N-term ●●●●...●●●●
Dye DYQ 660 - DYQ 660-NH N-term ●●●●...●●●●
Dye EDANS - CO-EDANS C-term ●●●●...●●●●
Dye Glu(EDANS) - [E(EDANS)] N-term, Internal, C-term ●●●●...●●●●
Dye His(DNP) - [H(DNP)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(2-(N-methylamino)benzoyl) - Lys(NMA) [Lys(NMA)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(2,4-DNP) - [K(DNP)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(5/6-Fluorescein) - [K(5/6-Fluo)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(5/6-TAMRA) - [K(5/6-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(5-Fluorescein) - [K(5-Fluo)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(5-TAMRA) - [K(5-TAMRA)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(6-Fluorescein) - [K(6-Fluo)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(Ahx-(5-Fluorescein)) - [K(Ahx-(5-Fluo))] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(ATTO 655) - [K(ATTO 655)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(Dabcyl) - [K(Dabcyl)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(Dde) - [Lys(Dde)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 405) - [K(DY 405)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 495) - [K(DY 495)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 530) - [K(DY 530)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 547) - [K(DY 547)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 590) - [K(DY 590)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 630) - [K(DY 630)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 635) - [K(DY 635)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 647) - [K(DY 647)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 650) - [Lys(DY 650)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DY 800) - [K(DY 800)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DyLight 488) - [K(DY 488)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DyLight 633) - Lys(DY633) [K(DyLight 633)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DyLight 649) - [K(DY 649)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(DYQ 3) - [K(DYQ 3)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(HOC) - (7-hydroxycoumarin-3-yl)formyl [Lys(HOC)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(HOMCA) - [Lys(HOMCA)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(MCA) - [K(MCA)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(MOC) - (7-methoxycoumarin-3-yl)formyl Lys(MOC) N-term, Internal, C-term ●●●●...●●●●
Dye Lys(Rhodamine B) - [K(Rhodamine B)] N-term, Internal, C-term ●●●●...●●●●
Dye Lys(Rhodamine Green) - [K(Rhodamine Green)] N-term, Internal, C-term ●●●●...●●●●
Dye Methoxycoumarin acetic acid - MCA CO-MCA C-term ●●●●...●●●●
Dye Methoxycoumarin acetic acid - MCA MCA-NH N-term ●●●●...●●●●
Dye Ornithine(Coumarin343) - [Orn(C343)] N-term, Internal, C-term ●●●●...●●●●
Dye para-Nitroanilide - pNA CO-pNA C-term ●●●●...●●●●
Dye para-Nitrophenylester - COONp C-term ●●●●...●●●●
Dye QSY21 - QSY21-NH N-term ●●●●...●●●●
Dye Rhodamine 110 - CO-Rhod 110 C-term ●●●●...●●●●
Dye Rhodamine B - Rhodamin B-NH N-term ●●●●...●●●●
Dye R-Phycoerythrin - CO- R-Phycoerythrin C-term ●●●●...●●●●
Dye Tide Quencher 2 - TQ2 TQ2-NH N-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis 3-Azido-Alanine - Aza [Aza] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis 5-Azidopentanoyl - 5-Azidovalerianoyl 5-Azidopentanoyl-NH N-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis 6-Azido-Norleucine - Nle(N3) [Nle(N3)] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Azidohomoalanine - Aha/ Dab(N3) [Aha] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Azido-Lysine - [K(N3)] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Cyclisation (C-C), disulfide - [C cyclo(S-S)] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Cyclisation (D-K), amide bond - [ ] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Cyclisation (E-K), amide bond - [ ] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Cyclisation (K-C-terminus) - side chain of K to C-terminus [ ] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Cyclisation (NH-CO), homodetic - [ ] N-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Double disulfide - [C cyclo(S-S)] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis D-Propargylglycine - D-Pra [D-Pra] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Hetero-Dimer - [ ] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Homo-Dimer - [ ] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Mixed amino acids - [X] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis para-Azido-Phenylalanine - [F(N3)] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Propargylalanine - alpha-Me-L-Ala(Pentynyl)-OH [Propargylala] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Propargylglycine - Pra [Pra] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Side chain coupling to Lys - Asymmetric Sequence [K] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Side chain coupling to Lys - Symmetric Sequence [K] N-term, Internal, C-term ●●●●...●●●●
Cyclization/Dimerization/Special Synthesis Site directed disulfide bridge - Cyclisation (C-C) [Cys cyclo(S-S)] N-term, Internal, C-term ●●●●...●●●●

FAQ

How many peptide modifications do you offer?

We support 1000+ peptide modifications spanning terminal modifications, side-chain functional group chemistry, PTMs, labels, linkers/PEG, lipidation, isotopes, and special amino acids. Use the searchable library below to filter by name, abbreviation, type, or position.

Is “functional group modification” the same as residue-selective chemistry?

Yes. In practice, “functional group modification” belongs under side-chain functional group modification (residue-selective chemistry), such as cysteine-specific thiol reactions, lysine-selective amine chemistry, and tyrosine-selective phenol chemistry.

What is included in cysteine-specific chemistry?

Typical cysteine-specific workflows include iodoacetamide/haloacetyl labeling, maleimide coupling, and disulfide formation/scrambling control—chosen based on whether you need a stable linkage or a reversible/cleavable connection.

Do modifications change purification and QC?

Often yes. Dyes, PEG, lipids, and bulky PTMs can change solubility and LC behavior. We align purification/QC (HPLC method choice and MS confirmation) to the modification to ensure the peptide is fit-for-purpose.

Do you provide monoisotopic mass / exact-mass confirmation?

Yes. We confirm identity by MS (monoisotopic / exact mass when applicable) and provide documentation (COA, chromatograms) appropriate to the construct.

How do you recommend specifying a modification request?

Send the sequence and indicate position (N-term, residue index/internal, or C-term) plus the desired modification/handle. If you’re unsure, state the application (imaging, capture, PK, stability, QC standard) and we’ll recommend a practical specification.

More FAQ'sAll FAQ's

Contact & quote request

For the fastest quote, send your peptide sequence(s), the desired modification/handle (or application goal), the modification position (N-term / residue index / C-term), quantity (mg), purity target, and intended use. We’ll recommend a practical specification and QC plan.

Fastest path
Request a Quote Browse modifications
Fast quote checklist
  • Sequence(s) + terminal state (free vs capped)
  • Desired modification/handle (or “recommend”)
  • Position (N-term / residue index / C-term)
  • Quantity + purity target + intended use
  • Any constraints (single-Cys, avoid multiple labeling, etc.)

Recommended reading

Use these as cross-links to deepen topical authority (and keep users on-site):

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