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Molecular Biology Services

Integrated molecular biology solutions spanning long RNA transcript services, mRNA transcription, gene synthesis, cloning and vector construction, plasmid DNA preparation, protein expression and purification, LNP formulation, and protein bioconjugation for research, biotechnology, and therapeutic development.

Overview

Modern molecular biology programs require reliable integration across DNA design, transcription, cloning, and protein production. Our Molecular Biology Services platform is designed to support this full workflow with flexible, high-quality solutions tailored to individual project needs.

Microgram to gram scale RNA production Gene to protein workflow Protein purification LNP formulation Bioconjugation ISO 9001:2015/ISO 13485:2016 U.S. Facilities in Texas

We provide end-to-end support from gene and nucleic acid synthesis through cloning, plasmid preparation, protein expression, and purification. At the center of this platform is our strongest service area: RNA and mRNA transcription, delivering high-quality transcripts for research, functional studies, and therapeutic development. A key advantage of our platform is scalable production, with the ability to support projects from microgram quantities for early-stage work to gram-scale production for larger development needs.

Integrated gene to protein workflow

A flexible workflow that supports projects from sequence design through purified recombinant product.

Molecular biology platform

Design • Transcribe • Express

A streamlined service platform for DNA, RNA, and protein workflows, built for reproducibility, scalability, and project flexibility.

RNA scale

µg to g

From screening quantities to gram-scale production

DNA services

Custom

Gene synthesis and vector construction

Expression

Flexible

Multiple host system support

Workflow

End-to-end

From sequence to purified product

Core Service Areas

Long RNA Transcript Services

Custom in vitro transcription services for long RNA and non-mRNA transcripts, supporting research and functional genomics workflows.

  • Long RNA transcript production
  • Custom IVT RNA synthesis
  • Template design and optimization
  • Research-grade RNA workflows

Request Long RNA Details

mRNA Transcription Services

Specialized mRNA synthesis services including capped, tailed, and modified mRNA for research and therapeutic development.

  • mRNA synthesis with capping options
  • Poly(A) tail incorporation
  • Modified nucleotide incorporation
  • IVT optimization workflows

Request mRNA Details

Gene & DNA Synthesis

Custom DNA and gene synthesis services for accurate sequence construction and downstream applications.

  • Custom gene synthesis
  • Codon optimization
  • Sequence engineering
  • Complex construct support

Request Gene Details

Cloning & Vector Construction

Precise construct assembly for research and expression workflows.

  • PCR cloning
  • Subcloning into vectors
  • Expression vector design
  • Sequence verification

Request Cloning Details

Plasmid DNA Preparation

High-quality plasmid DNA preparation for transfection and expression workflows.

  • Mini / Midi / Maxi prep
  • Endotoxin-free options
  • High-purity DNA
  • Ready-to-use formats

Request Plasmid Details

Protein Expression

Recombinant protein expression optimized for yield, solubility, and functionality.

  • Host system selection
  • Expression optimization
  • Yield improvement
  • Scalable workflows

Request Expression Details

Recombinant Protein Purification

High-purity protein purification using tailored chromatography strategies.

  • Affinity purification
  • Ion exchange
  • Size exclusion
  • Custom workflows

Request Purification Details

LNP Formulation

Lipid nanoparticle formulation for RNA and mRNA delivery applications.

  • LNP formulation for RNA payloads
  • Encapsulation optimization
  • Delivery-focused workflows
  • Research applications

Request LNP Details

Protein Modification & Bioconjugation

Custom protein modification and conjugation services for research and assay development.

  • Protein labeling
  • Site-specific conjugation
  • Linker and payload attachment
  • Functionalization strategies

Request Bioconjugation Details

Why This Platform Matters

RNA-Centered Strength

RNA and mRNA transcription services are positioned as the lead offering, reflecting strong demand and core platform capability.

Clear Service Structure

Each category is distinct and easy to understand, making it simple for customers to find the right technical starting point.

Scalable Project Support

From individual service requests to end-to-end workflows, the platform supports flexible project execution across multiple stages.

Contact & Quote Request

For the fastest quote, include your service area of interest, sequence or construct information, preferred scale, intended application, and any timeline requirements.

What to include

  • Service area needed
  • Sequence, construct, or template information
  • Scale and purity requirements
  • Application and project stage

Fastest path

Why Choose Bio-Synthesis

Trusted by biotech leaders worldwide for over 45+ years of delivering high quality, fast and scalable synthetic biology solutions.