Isotope-labeled peptides, cleavable linkers, and click-ready handles engineered for reproducible analytics and downstream chemistry.
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Bio-Synthesis provides precision labeling and functional handle peptide synthesis services for workflows that depend on accurate mass, predictable reactivity, and reproducible conjugation. Common applications include quantitative LC–MS standards, MS/MS validation peptides, targeted labeling (dyes/biotin/drugs), and modular assembly using click-ready chemistries.
Best-fit when you need
Uniform or residue-specific isotope placement.
Azide/alkyne workflows with minimal cross-reactivity.
Cleavable linkers tuned to your trigger and stability needs.
Use this table to map your project to the right labeling or handle strategy. For details, see the service sections below.
Related service pages (internal links)
For full options, pricing drivers, and examples, visit the dedicated pages:
Isotope-labeled peptide synthesis supports stable isotope dilution and method validation by incorporating defined isotopes and labeling patterns. Specify whether you need uniform labeling (entire peptide) or residue-specific labeling at defined positions.
Related: Isotope-labeled peptides service page.
Cleavable linker peptides incorporate linkers that break under defined conditions to release tags, payloads, or fragments. Specify the trigger and stability requirements so the linker performs reliably in your workflow.
Related: Cleavable linker peptides service page.
Click chemistry peptide synthesis installs azide/alkyne (or related) handles for modular conjugation. Tell us whether your downstream workflow uses copper-catalyzed click (CuAAC) or strain-promoted click (SPAAC) to guide handle selection and compatibility.
Related: Click chemistry peptides service page.
Provide the sequence, isotope(s) required, labeling pattern (uniform vs residue-specific), target purity/scale, and your analytical method (LC–MS, MS/MS, NMR).
Choose cleavable linkers when you need controlled release or traceless tag removal. Specify the trigger and required stability during storage and handling.
Yes. If copper is incompatible with your system, we can plan copper-free click strategies. Tell us your partner molecule and workflow constraints.
Yes. Provide the order of operations and any constraints; we can plan label placement and handle selection for compatibility.
Often. In addition to purity and LC–MS, projects may benefit from confirming labeling patterns, handle integrity, and linker stability/cleavage performance.
Tell us your storage conditions and buffer constraints. Some handles are sensitive to reducing agents, light, or specific pH ranges, and formulation can be adjusted accordingly.
Tip: If the peptide is hydrophobic/long/cysteine-rich, include that context so we can route the request to the right synthesis strategy.
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