Oligonucleotide synthesis with built-in flexibility, analytical quality, and dependable service support.
Bio-Synthesis provides flexible custom oligonucleotide manufacturing for DNA, RNA, modified oligos, and specialty constructs supporting research, diagnostic, and development workflows. Services include synthesis, scale-up production, purification, analytical QC, release testing, formulation, packaging, and custom delivery configurations tailored to program requirements.
Batch capability for scale-up programs
Standard, modified, and conjugated oligos
Flexible production scale options
Analytical testing and documentation support
Explore custom oligo services organized around the way scientists and program teams evaluate manufacturing partners: chemistry, scale, process development, formulation, packaging, QC, and support.
Primers, probes, long DNA oligos, capture oligos, labeled DNA constructs, and assay-ready DNA sequences for research and development workflows.
RNA oligos, siRNA, ASO, miRNA, guide RNA, aptamers, and modified RNA constructs with purification and analytical support.
Labels, quenchers, biotin, amino, thiol, azide, alkyne, phosphorothioates, LNA, 2′ modifications, and specialty conjugates.
Flexible synthesis and purification pathways for milligram, gram, and larger production needs with process and transfer support.
Custom workflows for novel chemistries, coupling optimization, deprotection strategy, purification development, and scale-up transfer.
Lyophilized or solution formats, target molarity, buffer selection, duplex annealing, aliquoting, and stability-oriented formulation options.
Tubes, plates, bulk fills, barcoded labels, kitting, OEM-ready formats, cold-chain options, and project-specific delivery configurations.
Analytical HPLC, LC-MS/MS support, PAGE, CE, endotoxin, bioburden, COA, batch records, and regulatory documentation options.
A clear end-to-end workflow helps align sequence requirements, process development, synthesis, purification, QC, formulation, packaging, and final shipment.
Bio-Synthesis supports demanding oligo programs with analytical testing, release documentation, and program-level quality support for research, diagnostic, and development workflows.
Custom oligos can be delivered in the format your program requires, reducing downstream handling and improving consistency across lots.
Bio-Synthesis brings decades of custom synthesis experience, broad modification capability, scalable manufacturing support, and analytical expertise to complex oligonucleotide programs.
Long-standing custom synthesis experience supporting research, biotechnology, diagnostic, and pharmaceutical organizations.
Broad support for labels, linkers, bases, backbone modifications, conjugates, and specialty oligo designs.
Support for early research lots through development-stage and regulated manufacturing discussions.
Purification, testing, documentation, and release packages aligned with project requirements.
Discuss sequence design, modifications, purification, scale-up, or QC requirements with our scientific team.
Submit your sequence, scale, modification, purification, and delivery requirements for project review.
Trusted by biotech leaders worldwide for over 45+ years of delivering high quality, fast and scalable synthetic biology solutions.