Advanced, chemistry-driven conjugation integrating linker design, payload attachment, and stoichiometry control across antibodies, proteins, peptides, and oligonucleotides—supported by LC-MS/HPLC analytics and ISO 9001/13485 quality.
Bio-Synthesis Inc. specializes in site-selective and multifunctional conjugation across a diverse range of biomolecules. We delivers custom bioconjugation across antibodies, proteins/peptides, oligonucleotides,small molecule, hapten and drug compound. We engineer linkers (cleavable/non-cleavable PEG, VC-PAB, disulfide, oxime/hydrazone) and run bioorthogonal chemistries (CuAAC, SPAAC/DBCO–Azide, IEDDA/TCO–Tetrazine) with control of substitution and site. Integrated analytics (LC-MS, UPLC/HPLC, SEC-MALS, DLS) and ISO 9001/13485-aligned documentation support scale-up from mg to kg for diagnostics and therapeutic research.
We design, execute, and qualify conjugations across biomolecules, chemistries, and formats—paired with robust analytics, documentation, and scale‑up so your materials are ready for research use and regulated pathways.
Orthogonal, high-yield coupling strategies optimized for activity preservation, site control, and clean analytics.
A transparent, science-first development cycle integrating design, feasibility, optimization, analytical qualification, and scale-up—streamlined for reproducibility and speed.
Immunoassays (ELISA, CLIA), lateral-flow labels, flow cytometry, IF/IHC, nucleic-acid detection probes, and QC controls.
Prototype ADCs/AOCs, targeted delivery, receptor occupancy, PK/PD tracking, and payload/linker evaluation.
Optical and nuclear imaging (PET/SPECT) via chelators (DOTA/NOTA/DTPA), ECL/redox tags for electrochemical biosensing.
Share your target, desired payload/label, and scale. Our scientists will respond with a feasibility plan and timeline.
Tell us about your biomolecule, desired label/payload, and intended use. We’ll recommend chemistry, linker design, and release testing to meet your goals.
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Trusted by biotech leaders worldwide for over 40+ years of delivering high quality, fast and scalable synthetic biology solutions.