Peptide Imaging Conjugates

Near-infrared dyes are often selected to reduce autofluorescence background and support deeper penetration in model systems. Selection depends on your instrument, detection windows, and sample type (project-dependent).

Radiolabel-compatible peptide conjugates incorporate metal-chelating ligands (chelators) that enable downstream coordination of radiometals for imaging or tracer studies. Bio-Synthesis provides non-radioactive chelator–peptide conjugates (chelator-enabled peptide precursors); we do not perform radiolabeling or handle radioactive materials. Feasibility and final chelator selection are project-dependent.

We support a broad range of chelator chemistries—including macrocyclic and related multidentate ligands—selected based on coordination requirements, charge profile, and downstream labeling conditions. Site-defined attachment (N-/C-terminus, single-Cys, or handle-enabled options) is used when feasible to improve reproducibility and preserve peptide function.

Tip: If you are comparing chelators, share your intended downstream radiometal and labeling conditions—we can propose a compatible chelator handle and a site-defined peptide attachment strategy (project-dependent).

Dual-label designs combine two labels (or a label plus an affinity/targeting element) to support multiplexed or correlative workflows. Architectures are planned to reduce steric interference and maintain peptide performance (project-dependent).